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Search Results for " atpase activity "

78

抑制剂 & 化合物

17

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T36816	S-trityl-L-Cysteine STLC	Kinesin	Cytoskeletal Signaling
	S-Trityl-L-cysteine 是别构驱动蛋白Eg5的选择性抑制剂。rityl-L-cysteine 抑制基础 ATPase 活性的IC50为 1 μM，抑制微管激活的 ATPase 活性的IC50为 140 nM。S-Trityl-L-cysteine 显示出抗肿瘤活性。
T17313	(+)-SJ733 SJ000557733	ATPase; Parasite	Membrane transporter/Ion channel; Microbiology/Virology
	(+)-SJ733 (SJ000557733) 是一种有效的 Na+-ATPase PfATP4 抑制剂，具有抗疟活性，可用于研究疟疾。
T20436	DHQ 2,3-dihydroxy-quinoxalin,2,3-二羟基喹喔啉	ATPase	Membrane transporter/Ion channel
	DHQ (2,3-dihydroxy-quinoxalin) 是单纯疱疹病毒胸苷激酶的 ATPase 活性诱导剂。
T14965	Ciliobrevin D	ATPase; Hedgehog/Smoothened	GPCR/G Protein; Membrane transporter/Ion channel; Stem Cells
	Ciliobrevin D 是细胞渗透性，可逆和特异性的 AAA + ATPase 运动细胞质动力蛋白抑制剂。它在体外抑制依赖于动力蛋白的微管滑动和 ATPase 活性。它抑制Hedgehog 信号和初级纤毛形成。
T3186	NU2058 O6-(Cyclohexylmethyl)guanine,O(6)-Cyclohexylmethylguanine	Topoisomerase; CDK	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	NU2058 (O(6)-Cyclohexylmethylguanine) 是一种基于鸟嘌呤的 CDK 抑制剂，抑制 CDK2 和 CDK1 的IC50值分别为 17 μM 和 26 μM。它也抑制 DNA 拓扑异构酶 II ATPase 活性，具有抗癌活性。
T12359	Paprotrain (alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile	Kinesin	Cytoskeletal Signaling
	Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) 是可渗透细胞的 kinesin MKLP-2的抑制剂，抑制 MKLP-2 的 ATPase 活性，IC50值为 1.35 μM，Ki 值为 3.36 μM。它对 DYRK1A 有中等的抑制作用，IC50值为 5.5 μM。
T16865	SCH28080	ATPase; Proton pump	Membrane transporter/Ion channel
	SCH28080 是一种可逆且具有 K+ 竞争性的胃 H+/K+-ATP 酶 (H+/K+-ATPase) 抑制剂，IC50 值为 20 nM (家兔微粒体膜)。SCH28080 在体内是有效的酸分泌抑制剂，具有抗溃疡活性、抗分泌和细胞保护活性。
T10693	CB-6644	Others	Others
	CB-6644 是 RUVBL1/2的选择性复合体抑制剂，能够抑制 RUVBL1/2 的 ATP 酶活性(IC50:15 nM)。它具有抗癌作用。
T21254	Vonoprazan Fumarate TAK-438,TAK 438,Vonoprazan Fumurate,TAK438,富马酸沃诺拉赞	Proton pump	Membrane transporter/Ion channel
	Vonoprazan Fumarate (TAK438) 是质子泵的有效抑制剂，是口服有效的高效钾竞争性酸阻断剂，具有抗分泌活性。在 pH 为 6.5 时，它抑制猪胃微粒体中的 H+,K+-ATPase 酶活性，IC50为 19 nM。它被开发用于研究酸相关疾病，如消化性溃疡和胃食管反流病。
T25770	116-9e MAL-2-11B,MAL2-11B,MAL211B,MAL 2 11B,MAL2 11B	Virus Protease	Microbiology/Virology
	116-9e (MAL2-11B) 是一种有效的 Hsp70 共伴侣 DNAJA1 抑制剂，具有抗病毒，抑制猿猴病毒40 (SV40) 的复制，抑制肿瘤抗原 (TAg) 内源性 ATP 酶活性和 TAg 介导的 Hsp70 激活。116-9e 可用于研究癌症耐药性。
T8901	YUM70	Apoptosis; GPR; HSP	Apoptosis; Cytoskeletal Signaling; Endocrinology/Hormones; GPCR/G Protein; Metabolism
	YUM70 是一种选择性葡萄糖调节蛋白 78 抑制剂，抑制全长蛋白的 GRP78 ATPase 活性的IC50值为 1.5 μM。它在胰腺癌中诱导内质网应激介导的细胞凋亡。
T5425	ML367	Epigenetic Reader Domain	Chromatin/Epigenetic
	ML367 是一种稳定的、有效的 ATPase 家族 AAA 结构域蛋白 5 抑制剂，是一个探针分子，具有低摩尔抑制浓度。它可以阻断 DNA 的修复通路，抑制一般的 DNA 损伤反应，包括应对紫外照射产生的 RPA32 和 CHK1 的磷酸化。
T9168	NSC 617145 NSC617145,NSC-617145	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	NSC 617145 (NSC617145) 是一种 WRN 解旋酶抑制剂，IC50值为 230 nM。它以浓度依赖性方式抑制 WRN 解旋酶的 ATP 酶，并诱导双链断裂和染色体异常。
T15146	DNA2 inhibitor C5	Others	Others
	DNA2 inhibitor C5 是竞争性特异性的DNA2 核酸酶活性抑制剂(IC50:20 μM)。它能够抑制DNA 依赖性 ATPase、 DNA2 的核酸酶、解旋酶和 DNA 结合活性。它可用于研究奥正癌症。
T83633	1-N-Methyl-4-mercaptohistidine disulfide	Others	Others
	1-N-Methyl-4-mercaptohistidine disulfide 是一种潜在的杜氏菌叶绿体偶联因子1氧化还原调节剂，是氧化形式的卵硫醇A，抑制光触发的CF1 ATP酶活性。
T10616	BRM/BRG1 ATP Inhibitor-1	Epigenetic Reader Domain	Chromatin/Epigenetic
	BRM/BRG1 ATP Inhibitor-1 是变构双 Brahma 同源物 (BRM)/SWI/SNF 相关的基质相关肌动蛋白依赖性调节剂，染色质亚家族 A 成员 2 和 BRG1/SMARCA4 ATP 酶活性抑制剂，IC50值低于 0.005 μM。
T10221	Abeprazan hydrochloride DWP14012 hydrochloride,Fexuprazan hydrochloride	Proton pump	Membrane transporter/Ion channel
	Abeprazan hydrochloride (Fexuprazan hydrochloride) 是一种有效的、可逆的、具有口服活性的potassium-competitive acid 阻滞剂，通过竞争性的与钾离子结合抑制 H+，K+- ATPase，而无需酸激活。Abeprazan hydrochloride 是一种质子泵抑制剂(PPI)，通过减少胃酸的产生而起作用，可用于治疗胃酸相关疾病，如胃食管反流病(GERD)和消化性溃疡。
T6929	Pantoprazole sodium Pantecta,泮托拉唑钠盐,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),泮托拉唑钠,BY-1023 sodium,Pantoloc	Apoptosis; Others; Proton pump; HIF; Autophagy	Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; Membrane transporter/Ion channel; Others
	Pantoprazole sodium (Pantecta) 是一种具有口服活性的质子泵抑制剂，是一种取代的苯并咪唑，是H+/K+-ATPase 抑制剂，IC50为 6.8 μM。它可以改善 pH 值稳定性，具有抗分泌和抗溃疡的作用。它联合阿霉素可显著增加肿瘤生长延迟。
T67951	JB061	Myosin	Cytoskeletal Signaling
	JB061是一种非肌肉肌球蛋白II抑制剂，针对心肌肌球蛋白、骨骼肌肌球蛋白和平滑肌肌球蛋白II的IC50分别为4.4 μM、9.1 μM和>100 μM。其对ATP酶活性的抑制作用较弱（IC50>200 μM）。此外，JB061对COS-7细胞显示出细胞毒性，IC50值为39 μM。
T0825	Ebselen SPI-1005,PZ-51,依布硒,CCG-39161	Phosphatase; Virus Protease; Calcium Channel; COX; HIV Protease	Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	Ebselen (CCG-39161) 是一种谷胱甘肽过氧化物酶模拟物，是电压依赖性钙通道阻断剂。它抑制Mpro 和COVID-19病毒，是HIV-1衣壳 CTD 二聚化的抑制剂，具有抗炎、抗癌和抗氧化活性。
T1756	Ilaprazole sodium IY-81149 sodium,艾普拉唑钠	Proton pump; TOPK	MAPK; Membrane transporter/Ion channel
	Ilaprazole sodium (IY-81149 sodium) 是一种具有口服活性质子泵抑制剂，以剂量依赖性方式不可逆地抑制 H+/K+-ATPase，在兔壁细胞制剂中的 IC50为 6 μM。它也是一种有效的 T 细胞起源蛋白激酶(TOPK)抑制剂，用于胃溃疡的研究。
T27184	Displurigen
	Displurigen is an inhibitor of ATPase activity of HSP70.
T78564	Depramine GP 31406
	Depramine (GP 31406) 是三环抗抑郁剂，具药理活性。该化合物可抑制乙酰胆碱酯酶、Mg2+-ATPase 与 Na+/K+ ATPase 活性。
T23978	Deox B 7,4 Deoxysappanone-B-7,4 dimethyl ether,Deox-B-7,4,Deoxysappanone B 7,4 dimethyl ether,DeoxB7,4
	Deox B 7,4 is a reversible microtubule inhibitor that acts by increasing lysosomal V-ATPase activity and lysosome acidity.
T30308	BDPSB
	BDPSB is a highly efficient photocontroller of mitotic kinesin Eg5 ATPase activity.
T40956	Eubananin
	Eubananin effectively inhibits the ATPase activity of the SARS Coronavirus helicase, displaying an IC50 value of 2.8 μM.
T30250	AZD0865 AZD-0865,AZD 0865
	AZD0865 is an effective drug that inhibits gastric H(+), K(+) -ATPase activity and acid formation in vitro, with rapid onset.
T61083	DN-F01
	DN-F01 exhibits a potent calcium-dependent inhibitory effect on cardiac myofibrillar ATPase activity, with an IC50 of 11 ± 4 nmol/L.
T40955	Vanillinbananin
	Vanillinbananin is a potent inhibitor of SARS Coronavirus helicase ATPase activity, displaying an IC50 value of 0.68 μM.
T40954	Iodobananin
	Iodobananin effectively inhibits the ATPase activity of the SARS Coronavirus helicase, displaying an IC 50 value of 0.54 μM.
T24785	S-Fcme S Fcme,SFcme
	S-Fcme is an activator of multidrug resistance transporter that acts by stimulating the multidrug resistance transporter ATPase activity and competing for drug binding.
T40767	Bananin
	Bananin, a potent inhibitor of the ATPase activity exhibited by the SARS Coronavirus helicase, demonstrates remarkable efficacy with an IC50 value of 2.3 μM.
T61553	ATPase-IN-2
	ATPase-IN-2 is a compound that acts as an inhibitor of ATPase, with an IC50 value of 0.9 μM. It also inhibits the glycohydrolase activity of C. difficile toxin B (TcdB) with an AC50 value of 30.91 μM. ATPase-IN-2 is commonly utilized in ATP-related research [1].
T61042	TBT1
	TBT1 是Acinetobacter 菌株中的 MsbA ATPase 刺激剂和LPS 转运抑制剂。TBT1 以13 μM 的 EC50 值刺激 ATPase 活性。TBT1 是MsbA 转运蛋白的一代抑制剂。
T71271	RL71
	RL71 is a sselective inhibitor of SERCA2, specially binding to SERCA2 at a novel site, suppressing the Ca2+-ATPase activity of SERCA2, inducing apoptosis and downregulating Akt.
T37685	CAY10719 CAY10719
	CAY10719 is a selective inhibitor of the breast cancer resistance protein ABCG2 (IC50 = 0.23 μM) with little activity at ABCG1. It has been shown to reverse the ABCG2-mediated resistance toward SN 38 and to inhibit ATPase activity.
T37707	14-Anhydrodigitoxigenin
	14-Anhydrodigitoxigenin is a cardenolide and a derivative of digitoxin.1 It reduces the activity of guinea pig heart Na+/K+-ATPase by 15% when used at a concentration of 10 μM.2
T13076	Tamoxifen-d5 ICI 47699-d5,(Z)-Tamoxifen-d5,trans-Tamoxifen-d5	HSP	Cytoskeletal Signaling; Metabolism
	Tamoxifen-d5 is a deuterium labeled Tamoxifen. Tamoxifen is a selective modulator of estrogen receptor (SERM). Tamoxifen is a potent activator of Hsp90 and enhances the Hsp90 molecular chaperone ATPase activity.
T28156	Nepaprazole TY-11345,TY11345,TY 11345
	Nepaprazole is a proton pump inhibitor. TY-11345 potently inhibited H+/K(+)-ATPase activity in isolated rabbit gastric mucosal microsomes, and the inhibitory effect was enhanced under weak acid conditions, the IC50 being 5.8 microM and 9.9 microM at pH 6.
T35465	(±)16-HETE
	Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (±)16-HETE is the racemic version of a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation. The biological activity of 16-HETE is stereospecific. 16(R)-HETE dose-dependently stimulates vasodilation of the rabbit kidney, however 16(S)-HETE does not affect perfusion pressure. At a concentration of 2 μM the (S)-enantiomer of 16-HETE inhibits pro...
T73050	KIF18A-IN-7
	KIF18A-IN-7 是一种具有口服活性的 KIF18A 抑制剂，抑制 KIF18A 微管依赖性 ATPase 活性，IC50为 9.4 nM。
T60469	Chloroprocaine
	Chloroprocaine (2-Chloroprocaine) 是一种有效的Na，K-ATPase 酶活性抑制剂（IC50 = 13 mM）。Chloroprocaine 是一种阻滞外周神经的局部麻醉剂。
T80297	Aurein 2.3	Antibiotic	Microbiology/Virology
	Aurein 2.3为一种抗生素抗菌肽，能部分抑制大肠杆菌的ATP酶活性并阻止细菌生长。
T71527	NSC145366
	NSC145366 is an inhibitor of Hsp90 activities which targets the Hsp90 C-terminal domain to induce allosteric inhibition and selective client downregulation. NSC145366 increases Hsp90 oligomerization resulting in allosteric inhibition of NTD ATPase activity (IC50=119μM) but does not compete with NTD or CTD-ATP binding.
T74377	Ansabananin
	Ansabananin 是一种 SARS 病毒解旋酶 ATP 酶活性的抑制剂，其IC50为 51 μM。
T72921	Reversin 121
	Reversin 121为P-糖蛋白(P-glycoprotein) 抑制剂，能增加MDR1的ATP酶活性，可逆转P-糖蛋白介导的多药耐药性，适用于癌症研究。
T61445	Tenatoprazole sodium
	Tenatoprazole sodium (TU-199 sodium) is a potent proton pump inhibitor that effectively suppresses the activity of hog gastric H+/K+-ATPase, a vital enzymatic pump involved in acid secretion. It achieves this inhibition at an impressive IC50 value of 6.2 μM.
T35848	16(S)-HETE
	Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 16-HETE is a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. 16(S)-HETE inhibits proximal tubule ATPase activity by as much as 60% at a concentration of 2 μM.
T70628	Cmpd-A
	Cmpd-A is a time-dependent CENP-E inhibitor with potent antitumor activity. Cmpd-A inhibits the ATPase activity of the CENP-E motor domain, acting as a time-dependent inhibitor with an ATP-competitive-like behavior. Cmpd-A causes chromosome misalignment on the metaphase plate, leading to prolonged mitotic arrest. Treatment with Cmpd-A induces antiproliferation in multiple cancer cell lines.
T75360	Oxonol VI
	Oxonol VI 是一种膜电位的光学指示剂，在脂质囊泡中发挥作用。它能用于监测重组囊泡中与 (Na++K+)-ATPase 活性相关的膜电位变化。

化合物

S-trityl-L-Cysteine

Cat.No: T36816

Synonym: STLC

Target: Kinesin

Cat.No: T17313

Synonym: SJ000557733

Target: ATPase, Parasite

Cat.No: T20436

Synonym: 2,3-dihydroxy-quinoxalin,2,3-二羟基喹喔啉

Target: ATPase

Cat.No: T14965

Target: ATPase, Hedgehog/Smoothened

Cat.No: T3186

Synonym: O6-(Cyclohexylmethyl)guanine,O(6)-Cyclohexylmethylguanine

Target: Topoisomerase, CDK

Cat.No: T12359

Synonym: (alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile

Target: Kinesin

Cat.No: T16865

Target: ATPase, Proton pump

Cat.No: T10693

Target: Others

Vonoprazan Fumarate

Cat.No: T21254

Synonym: TAK-438,TAK 438,Vonoprazan Fumurate,TAK438,富马酸沃诺拉赞

Target: Proton pump

Cat.No: T25770

Synonym: MAL-2-11B,MAL2-11B,MAL211B,MAL 2 11B,MAL2 11B

Target: Virus Protease

Cat.No: T8901

Target: Apoptosis, GPR, HSP

Cat.No: T5425

Target: Epigenetic Reader Domain

Cat.No: T9168

Synonym: NSC617145,NSC-617145

Target: DNA/RNA Synthesis

DNA2 inhibitor C5

Cat.No: T15146

Target: Others

1-N-Methyl-4-mercaptohistidine disulfide

Cat.No: T83633

Target: Others

BRM/BRG1 ATP Inhibitor-1

Cat.No: T10616

Target: Epigenetic Reader Domain

Abeprazan hydrochloride

Cat.No: T10221

Synonym: DWP14012 hydrochloride,Fexuprazan hydrochloride

Target: Proton pump

Pantoprazole sodium

Cat.No: T6929

Synonym: Pantecta,泮托拉唑钠盐,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),泮托拉唑钠,BY-1023 sodium,Pantoloc

Target: Apoptosis, Others, Proton pump, HIF, Autophagy

Cat.No: T67951

Target: Myosin

Cat.No: T0825

Synonym: SPI-1005,PZ-51,依布硒,CCG-39161

Target: Phosphatase, Virus Protease, Calcium Channel, COX, HIV Protease

Ilaprazole sodium

Cat.No: T1756

Synonym: IY-81149 sodium,艾普拉唑钠

Target: Proton pump, TOPK

Cat.No: T27184

Cat.No: T78564

Synonym: GP 31406

Cat.No: T23978

Synonym: Deoxysappanone-B-7,4 dimethyl ether,Deox-B-7,4,Deoxysappanone B 7,4 dimethyl ether,DeoxB7,4

Cat.No: T30308

Cat.No: T40956

Cat.No: T30250

Synonym: AZD-0865,AZD 0865

Cat.No: T61083

Vanillinbananin

Cat.No: T40955

Cat.No: T40954

Cat.No: T24785

Synonym: S Fcme,SFcme

Cat.No: T40767

Cat.No: T61553

Cat.No: T61042

Cat.No: T71271

Cat.No: T37685

Synonym: CAY10719

14-Anhydrodigitoxigenin

Cat.No: T37707

Cat.No: T13076

Synonym: ICI 47699-d5,(Z)-Tamoxifen-d5,trans-Tamoxifen-d5

Target: HSP

Cat.No: T28156

Synonym: TY-11345,TY11345,TY 11345

Cat.No: T35465

Cat.No: T73050

Cat.No: T60469

Cat.No: T80297

Target: Antibiotic

Cat.No: T71527

Cat.No: T74377

Cat.No: T72921

Tenatoprazole sodium

Cat.No: T61445

Cat.No: T35848

Cat.No: T70628

Cat.No: T75360

Cat. No.	Product Name	Target	Signaling Pathways
T3432	Cinobufagin 华蟾蜍精,华蟾酥毒基,Cinobufagine	Apoptosis; ATPase; Autophagy	Apoptosis; Autophagy; Membrane transporter/Ion channel
	Cinobufagin (Cinobufagine) 是一种具有抗肿瘤功效的天然产物。
TN1860	Licoflavone B 甘草黄酮 B,甘草黄酮B	ATPase; Anti-infection; Parasite	Membrane transporter/Ion channel; Microbiology/Virology
	Licoflavone B 是从甘草中得到的一种类黄酮，抑制曼氏血吸虫 ATPase 和 ADPase 的活性，IC50值分别为 23.78 µM 和 31.50 µM。
TQ0184	Chebulinic acid	ATPase; Proton pump; DNA/RNA Synthesis; Antibacterial; TGF-beta/Smad	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology; Stem Cells
	Chebulinic acid 是从诃子果中提取的一种天然产物，结核分枝杆菌 DNA 促旋酶的有效抑制剂。它也能抑制 SMAD-3 phosphorylation 和 H+ K+-ATPase 的活性。
T6062	Brefeldin A BFA,布雷非德菌素 A,Ascotoxin,Cyanein,Decumbin	ATPase; Mitophagy; Antibiotic; Autophagy; HSV; CRISPR/Cas9	Autophagy; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology
	Brefeldin A (Cyanein) 属于大环内酯类抗生素，是一种 ATPase 抑制剂 (IC50=0.2 μM)。Brefeldin A 可以诱导肿瘤细胞分化和凋亡，也具有抑制自噬的活性。
T3926	Echinatin 刺甘草查尔酮,Retrochalcone	Free radical scavengers	oxidation-reduction
	Echinatin (Retrochalcone) 是分离自中草药甘草中，具有保肝和抗炎活性。在大鼠中，它可以被快速吸收和消除，并广泛分布，绝对生物利用度约为 6.81％。
T0974	Novobiocin Sodium Albamycinsodium,新生霉素钠,Cathomycin,Albamycin	Potassium Channel; DNA gyrase; Topoisomerase; Antibacterial; Antibiotic; ABC; Autophagy	Autophagy; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology
	Novobiocin Sodium (Albamycinsodium) 是源自 Streptomyces niveus 的抗生素。它的化学结构类似于香豆素。Novobiocin 与 DNA 促旋酶结合并阻断三磷酸腺苷活性。
T5S0890	Oleandrin Neriostene,Folinerin,Foliandrin,欧夹竹桃苷	Apoptosis; ATPase; Potassium Channel; Sodium Channel	Apoptosis; Membrane transporter/Ion channel
	Oleandrin (Folinerin) 是夹竹桃属中的一种类固醇，可抑制Na+/K+-ATPase 活性，IC50为 620 nM。
T3868	Agnuside 牡荆油,穗花牡荆苷,chasteberry oil	COX; Prostaglandin Receptor; P-gp	GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience
	Agnuside (chasteberry oil) 是从黄荆中分离得到的一种天然产物，可下调炎性介质PGE2和LTB4，减少细胞因子的表达，具有抗关节炎活性。
T1719	Bufalin	ATPase	Membrane transporter/Ion channel
	Bufalin 是蟾酥中的一种成分，是Na+/K+-ATPase 抑制剂，具有抗肿瘤活性，可与其基 α1、α2 和 α3 结合，Kd 值分别为 42.5、45 和 40 nM。
T7190	Actein	Apoptosis; Akt; JNK; Autophagy	Apoptosis; Autophagy; Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling
	Actein 是从升麻的根茎中分离的一种三萜糖苷，通过促进ROS/JNK 活化和钝化人膀胱癌中的AKT 途径来抑制细胞增殖，诱导自噬和凋亡。
T6S1049	Wilforine	ATPase	Membrane transporter/Ion channel
	Wilforine 是一倍半萜吡啶化合物，T. wilfordii 植物中的重要生物活性化合物，可有效治疗特发性肺纤维化。它具有抗炎和杀虫活性。
T5075	Phytic acid potassium 植酸二钾盐,Inositol hexakisphosphate dipotassium salt,Phytic acid dipotassium salt,Fytic Acid dipotassium salt,Inositol polyphosphate dipotassium salt	Others; Endogenous Metabolite	Metabolism; Others
	Phytic acid potassium (Inositol polyphosphate dipotassium salt) 是内源性代谢产物的一种。
T38609	Mycalolide B
	Mycalolide-B is a marine sponge-derived compound that functions as a selective inhibitor of actomyosin ATPase. It effectively hinders ATP-induced contraction and Mg2+-ATPase activity in the absence of Ca2+.
TN3914	Echinatine	ATPase; IL Receptor; TNF	Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel
	Echinatin exerts a protective effect against ischemia/reperfusion (I/R)-induced myocardial injury on hearts, this effect may be attributed to the antioxidant and anti-inflammatory activities of this compound. Echinatin can inhibit DNP-ATPase activity whil
T23610	Acerinol
	Acerinol is an active ingredient from traditional Chinese medicinal herbs. It could be used as a cancer multidrug resistance reversal agent. Acerinol can significantly stimulate the activity of ABCB1 ATPase without affecting the expression of ABCB1 on nei
T72645	Norbatzelladine L
	Norbatzelladine L 是一种 Pdr5p 转运蛋白催化活性和功能活性的抑制剂。Norbatzelladine L 抑制 Pdr5p ATPase 活性，IC50值为 3.8 µM。Norbatzelladine L 具有抗真菌 (antifungal)、抗寄生虫 (antiparasitic)、抗病毒 (antiviral)、抗细菌 (antibacterial) 和抗肿瘤活性。
T35779	Oosporein
	Oosporein is a mycotoxin that has been found inBeauveriaand has diverse biological activities.1,2It is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of 4.23 and 10.43 μM, respectively.3Oosporin induces lethality in day-old cockerels (LD50= 6.12 mg/kg).4It inhibits Na+/K+-, Ca2+-, and Mg2+-ATPase activities by 27, 52, and 100%, respectively, in equine erythrocyte ghosts when used at a concentration of 200 μg/ml.2Oosporein inhibits herpes simplex 1 (HSV-1), ...

天然产物

Cat.No: T3432

Synonym: 华蟾蜍精,华蟾酥毒基,Cinobufagine

Target: Apoptosis, ATPase, Autophagy

Cat.No: TN1860

Synonym: 甘草黄酮 B,甘草黄酮B

Target: ATPase, Anti-infection, Parasite

Chebulinic acid

Cat.No: TQ0184

Target: ATPase, Proton pump, DNA/RNA Synthesis, Antibacterial, TGF-beta/Smad

Cat.No: T6062

Synonym: BFA,布雷非德菌素 A,Ascotoxin,Cyanein,Decumbin

Target: ATPase, Mitophagy, Antibiotic, Autophagy, HSV, CRISPR/Cas9

Cat.No: T3926

Synonym: 刺甘草查尔酮,Retrochalcone

Target: Free radical scavengers

Novobiocin Sodium

Cat.No: T0974

Synonym: Albamycinsodium,新生霉素钠,Cathomycin,Albamycin

Target: Potassium Channel, DNA gyrase, Topoisomerase, Antibacterial, Antibiotic, ABC, Autophagy

Cat.No: T5S0890

Synonym: Neriostene,Folinerin,Foliandrin,欧夹竹桃苷

Target: Apoptosis, ATPase, Potassium Channel, Sodium Channel

Cat.No: T3868

Synonym: 牡荆油,穗花牡荆苷,chasteberry oil

Target: COX, Prostaglandin Receptor, P-gp

Cat.No: T1719

Target: ATPase

Cat.No: T7190

Target: Apoptosis, Akt, JNK, Autophagy

Cat.No: T6S1049

Target: ATPase

Phytic acid potassium

Cat.No: T5075

Synonym: 植酸二钾盐,Inositol hexakisphosphate dipotassium salt,Phytic acid dipotassium salt,Fytic Acid dipotassium salt,Inositol polyphosphate dipotassium salt

Target: Others, Endogenous Metabolite

Cat.No: T38609

Cat.No: TN3914

Target: ATPase, IL Receptor, TNF

Cat.No: T23610

Norbatzelladine L

Cat.No: T72645

Cat.No: T35779

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